Immunohistochemical findings of osteopontin expression in various odontogenic cyst and odontogenic tumour: A systematic review

Objective: This study aimed to assess osteopontin expression following immunohistochemical staining of odontogenic cysts and tumors. Methods: A systematic review was conducted based on PRISMA Statement. The literature search carried out through PubMed, Scopus, Science Direct databases, covering all the articles published up October 2021, using a combination key terms ‘osteopontin’, ‘odontogenic tumor’, cyst’, ‘expression’. tool Joanna Briggs Institute Critical Appraisal Checklist for Cross Sectional Studies applied examine quality selected articles. Results: strategy yielded in total 853 possibly relevant references. After removal duplicates, 614 titles abstracts were initially reviewed. From these, 22 independently assessed full text eligibility, seven studies included review. analysis revealed frequency as 35.3% (-) score, 23.5% (+) 21.6% (++) 19.6% (+++) score; tumors 11.3% 1.9% 3.8% 83% score. Conclusions: present showed different between OPN with score tumor higher than that cyst. highest shown cysts. Osteopontin has pattern related progressivity recurrence lesion.